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劉立強(知名專家)

主任醫(yī)師 教授 博士生導師

專家門診: 電 話:010-53968000

個人簡介

  會陰整形與性別重塑中心主任,北京協(xié)和醫(yī)學院教授博士研究生導師,中國醫(yī)學科學院整形外科醫(yī)院主任醫(yī)師,中華醫(yī)學會整形外科分會會員,國際美容整形外科學會會員(ISAPS),美國耶魯大學、哈佛大學、加利福尼亞大學洛杉磯分校整形外科中心訪問學者,比佛利山Medical Tower客座教授。美國 Journal of Plastic   and Reconstructive Surgery 和 Journal of Aesthetic Plastic Surgery 雜志特約審稿人。


  臨床醫(yī)療:主要從事各種原因?qū)е碌娜梭w體表組織器官畸形及缺失的臨床修復重建工作,擅長應用顯微和擴張皮瓣修復大面積體表組織缺損和器官再造,尤其在會陰整形及性器官再造方面有獨特造詣。熟練掌握:1、顯微外科技術(shù):以顯微外科技術(shù)和原則指導的復雜多組織遠位游離吻合血管及微創(chuàng)修復操作。2、整形外科技術(shù):以整形外科技術(shù)和原則無創(chuàng)無張力指導的內(nèi)在功能與外觀形態(tài)兼顧的修復理念。3、皮膚組織擴張技術(shù):以美觀為指導的就近擴張及靈活多變的擴張皮瓣移植轉(zhuǎn)移方法。


  臨床主要解決:1、泌尿生殖及肛門部位的先天性畸形(尿道下裂、陰道閉鎖、肛門閉鎖)、外傷及感染后的瘺與竇道、肛門失禁、盆底松弛。2、真假兩性畸形及跨性別畸形的性器官再塑造,以及性別重塑后的五官輪廓和體形雕塑。3、體表創(chuàng)傷瘢痕及先天性胎記的修復,尤其對于復雜的面部及會陰部的毀損性畸形有豐富經(jīng)驗。4、醫(yī)學美容:雙眼皮成形、瞼袋切除、鼻成形、腹壁成形、除皺、面部年輕化手術(shù);失敗的美容手術(shù)修復;隆胸與乳房下垂矯正;吸脂與脂肪移植技術(shù)。


  科學研究2001年參與衛(wèi)生部臨床學科重點項目“尿道下裂綜合治療的研究”。2002年承擔國家自然基金“組織工程化尿道的研究”中種子細胞的培養(yǎng)與動物實驗部分研究工作。2012年主持完成人事部留學基金“鼠皮膚干細胞空間分布規(guī)律研究”。2015主持完成院所基金課題“攜帶神經(jīng)肌肉支配及闊筋膜再造白膜的犬功能陰莖再造術(shù)”。2018年6月-2022年6月主持首都特色臨床項目“動態(tài)功能性陰莖再造的臨床應用研究”。2021年9-2023年10月主持中國醫(yī)學科學院科技創(chuàng)新項目“三維掃描技術(shù)在頸部瘢痕攣縮精準治療中的應用”。2021年一月-2022年一月院所基金“假兩性畸形家系的基因遺傳學研究”及“組織工程陰莖海綿體的構(gòu)建”。2024年1月開始主持首都發(fā)展專項課題“基于真皮血管三維可視化的跨區(qū)皮瓣遠端靜脈淤血機制研究”。


  創(chuàng)立技術(shù)與臨床應用

  1. 女假兩性畸形保留完整性敏感度的陰唇陰蒂重建術(shù)。Staged Reconstruction of the Labia Minora and Reduction Clitoroplasty for Female Pseudohermaphroditism. Aesth Plast Surg (2010) 34:652–656. https://pubmed.ncbi.nlm.nih.gov/20414773/

  2、自主勃起動力的股薄肌動態(tài)陰莖再造技術(shù),無需假體植入即獲得陰莖硬度和活動功能

  ①The pedicled gracilis muscle combined with the fascia lata: a preliminary clinical study of a new biomimetic dynamic phalloplasty method. The Journal of Sexual Medicine. 2023-01-12.DOI:10.1093/jsxmed/qdac022. 

https://pubmed.ncbi.nlm.nih.gov/36763921/

  ②Dynamic Penile Corpora Cavernosa Reconstruction Using Bilateral Innervated Gracilis Muscles: A Preclinical Investigation. Sex Med. 2018 Jun; 6(2): 162–170.

  ③基于逆行設(shè)計方法的陰莖頭成形術(shù)在陰莖再造中的臨床應用。2023.39(6):621-627. 

  3、面部毀損性瘢痕畸形的美容性修復技術(shù),擴張與顯微技術(shù)結(jié)合,皮膚與骨復合移植

  ①Aesthetic Design of Expanded Bilateral Superficial Temporal Vascular Fascial Pedicled Flap for Repairing Maxillocervical Scars. Annals of Plastic Surgery. 2021 Nov 1;87(5):509-513 1.2 

  ②Different Transfer Forms of the Expanded Forehead Flap Pedicled With Superficial Temporal Vessels to Treat Chin and Submental Scar Deformities. Journal of Craniofacial Surgery. 2022 Jun 1;33(4):1066-1070 1.3  

  ③A Reversal Forehead Free Flap Transplantation Without Interrupted Perfusion for Esthetic Repairing the Mentocervical Scar Deformity. Journal of Craniofacial Surgery. 2022 Aug 15 1.4

  ④The Transfer of Expanded Forehead Superthin Flap Without Frontalis and Less Hair Follicles Pedicled by Superficial Temporal Vessels. Ann Plast Surg. 2023 Feb 1;90(2):128-132。


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  4、自體條狀軟骨移植隆鼻技術(shù),肋軟骨和耳廓軟骨均可以采用

  Augmetation of the nasal dorsum using the multistrip autologous cartilage technique. Plastic and Reonstructive Surgey,2017, 140(6):1163-1166. 


微信圖片_20240301121621.png


  5、鼻頭肥大矯治應用軟骨交叉縮小成形術(shù),解決鼻頭寬大下垂及部分鼻孔外露

  Broad Tip Modification in Asian Patients Undergoing Rhinoplasty Using the Low-Lateral Cartilage Cruciate Overlap Technique. JAMA Facial Plast Surg. 2015 Jul-Aug;17(4):279-85。


微信圖片_20240301121638.png


  6. 無創(chuàng)面腭裂修復技術(shù)Use of the buccinator musculomucosal flap for bone coverage in primary cleft palate repair.. Aesthetic Plast Surg. 2013 Dec;37(6):1171-5.


微信圖片_20240301121741.png


  7.無痕內(nèi)眼角開大技術(shù)

  ①Three-Dimensional Z-Epicanthoplasty Retains the Depth of the Medial Canthus With Scars That Are Less Visible. Annals Plastic surgery. 2022 Jul 1;89(1):17-22. DOI:10.1097/sap.0000000000003209

  ②Inverted ‘V-Y’ advancement medial epicanthoplasty. Journal of Plastic, Reconstructive & Aesthetic Surgery (2012) 65, 43-47.


微信圖片_20240301121817.png


  8. 完全保留輪匝肌的仿生無痕切開重瞼成形術(shù) 眼輪匝肌淺深層肌膜釋放和眶隔高位重置在切開重瞼術(shù)中的應用,中華整形外科雜志2019,35(6):533-537。

  9. 美容性鬢角再造技術(shù)

  耳后皮膚頭皮聯(lián)合擴張皮瓣鬢角再造術(shù),中華整形外科雜志, 2019,35(5):425-429。


微信圖片_20240301121854.png


  10.筋膜肌肉懸吊糾正上瞼皮膚松弛,同時改善額部橫紋真皮筋膜肌肉懸吊在上瞼皮膚提升和隆眉弓中的應用,中華醫(yī)學美學美容雜志,2019,25(6)13.468-470.


微信圖片_20240301121915.png


  11. 尿瘺修復技術(shù)

  整形外科學原則在尿瘺修復中的應用。中華泌尿外科雜志。2006:27(2):131 – 134。

  12.神經(jīng)纖維瘤皮膚回植治療巨大神經(jīng)纖維瘤

  Total resection of giant plexiform neurofibroma of the entire back in one stage by autologous tumor skin graft. J Plast Reconstr Aesthet Surg.2012 Feb;65(2):276-7.

  13. 尿道下裂修復術(shù)后形態(tài)與功能學研究。首屆臨床泌尿外科雜志國際學術(shù)會議2005,北京。

  14.中國漢族懸膽鼻審美的演變與進展。中華醫(yī)學美學美容雜志》。2020年第5期361-363。首次提出以懸膽鼻為審美標準的鼻成形術(shù)。


1709268698218.png


  15.面部巨痣治療


微信圖片_20240301124549.png


  16.面部年輕化,高位SMAS筋膜懸吊術(shù)


微信圖片_20240301124615.png


  17.嚴重肢體多關(guān)節(jié)瘢痕攣縮畸形修復


微信圖片_20240301124640.png


  18.上瞼生物力學原理與結(jié)構(gòu)重建修復重瞼術(shù)后畸形Outer Fascia of Orbicularis Oculi Muscle (OFOOM)-Orbicularis (OOM)-Aponeurosis Fixation Approach in Double-Eyelid Blepharoplasty Revision. Aesth Plast Surg. 2023 Nov 22.doi: 10.1007/s00266-023-03731-2.

https://doi.org/10.1007/s00266-023-03731-2


微信圖片_20240301124703.png


  科研成果:

  2006年獲中華醫(yī)學科技獎三等獎。

  發(fā)表論文40余篇,參與編寫專著3部,主譯1部。主要論文: 

  1.Liqiang Liu. Jincai Fan, Tianjia,et al. Staged Reconstruction of the Labia Minora and Reduction Clitoroplasty for Female Pseudohermaphroditism. Aesth Plast Surg (2010) 34:652–656

  2.Liqiang  Liu. Jincai Fan, Gancheng, et al.  Total resection of giant plexiform neurofibroma of the entire back in one stage by autologous tumor skin graft.J Plast Reconstr Aesthet Surg.2012 Feb;65(2):276-7.

  3.Liqiang Liu. Sheng Li,Jincai Fan,et al. Inverted ‘V-Y’ advancement medial epicanthoplasty. Journal of Plastic, Reconstructive & Aesthetic Surgery (2012) 65, 43-47.

  4. Yang Z, Liu L(corresponding author), Fan J, Chen W, Fu S, Yin Z. Use of the buccinator musculomucosal flap for bone coverage in primary cleft palate repair.. Aesthetic Plast Surg. 2013 Dec;37(6):1171-5.

  5. Yin Z, Liu L(corresponding author), Fan J, Tian J,et al. Broad Tip Modification in Asian Patients Undergoing Rhinoplasty Using the Low-Lateral Cartilage Cruciate Overlap Technique. JAMA Facial Plast Surg. 2015 Jul-Aug;17(4):279-85.

  6.Yin Z, Liu L(corresponding author).Dynamic Penile Cavernosa Reconstruction Using Bilateral Innervated Gracilis Muscle: A Preclinical Investigation. Plast Reconstr Surg. 2015 Oct;136(4 Suppl):75-6.

  7. Zhang T, Liu L(corresponding author), Fan J,et al.Low-level laser treatment stimulates hair growth via upregulating Wnt10b and β-catenin expression in C3H/HeJ mice. Lasers Med Sci. 2017 May 16.

  8. Liqiang Liu. Zhaoyun B. Fan J, et al.Augmetation of the nasal dorsum using the multistrip autologous cartilage technique. Plastic and Reonstructive Surgey,2017,140(6):1163-1166. 

  9. Yin Z, Liu L(corresponding author), Fan J, Tian J,et al. Dynamic Penile Corpora Cavernosa Reconstruction Using Bilateral Innervated Gracilis Muscles: A Preclinical Investigation. Sex Med. 2018 Jun; 6(2): 162–170.

  10.Infraeyebrow Blepharoplasty Using Dynamic Suspension Technique Between Dermis-Fascia Flap and Frontalis in Upper Eyelid Lifting and Eyebrow Augmentation.J Craniofac Surg. 2022 Mar-Apr 01;33(2):624-627. doi: 10.1097/SCS.0000000000008139.

  11.Aesthetic Design of Expanded Bilateral Superficial Temporal Vascular Fascial Pedicled Flap for Repairing Maxillocervical Scars. Ann Plast Surg 2021;87: 509–513).

  12.Different Transfer Forms of the Expanded Forehead Flap Pedicled with Superficial Temporal Vessels to Treat Chin and Submental Scar Deformities.J Craniofac Surg.2021 Dec 8. doi: 10.1097/SCS.0000000000008412.

  13.Low-level laser treatment promotes skin wound healing by activating hair follicle stem cells in female mice Lasers Med Sci. 2022 Apr;37(3):1699-1707. doi: 10.1007/s10103-021-03419-6.

  14. Three-Dimensional Z-Epicanthoplasty Retains the Depth of the Medial Canthus With Scars That Are Less Visible. Ann Plast Surg 2022;89: 17–22. DOI: 10.1097/SAP.0000000000003209

  15.Bioinformatics analysis and verification of hub genes in 46,XY, disorders of sexual development. Reprod Fertil Dev. 2023 Feb 14

  16.A Preliminary Study of Constructing the Tissue-Engineered Corpus Cavernosum With Autologous Adipose Stem Cells In Vivo. Sexual Medicine. 10(5) 100563.DOI:10.1016/j.esxm.2022.100563

  17. Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients:A multicentre cohort study. Int Wound J. 2023;1–9. https://orcid.org/0000-0001-5448-6868.

  18. Epidemiology and Predictors for Cervical Burn Scar Contractures: A Multicenter Cohort Study. J Craniofac Surg 2023;00: 000–000. DOI: 10.1097/SCS.0000000000009344

  19.A Reversal Forehead Free Flap Transplantation Without Interrupted Perfusion for Esthetic Repairing the Mentocervical Scar Deformity. J Craniofac Surg. 2022 Aug 15. doi: 10.1097/SCS.0000000000008896.

  20..Faciocervical Reconstruction Using a Large Expanded Forehead Island Flap Grafted Using a Microsurgical Technique for Burned Cicatricial Contracture Correction. J Craniofac Surg. 2018 Oct;29(7):1848-1850.doi: 10.1097/SCS.0000000000004647. 

  21.Reconstruction of large unilateral hemi-facial scar contractures with supercharged expanded forehead flaps based on the anterofrontal superficial temporal vessels. Journal of plastic, reconstructive & aesthetic surgery. 2013(66) 11:1470-6。

  22.Aesthetic Mental and Cervical Reconstruction After Severe Acne Inversa by Using a Bilateral Pedicled Expanded Forehead Flap. The Journal of craniofacial surgery. 2012, 23(6):e615-7.

  23. Aesthetic full-perioral reconstruction of burn scar by using a bilateral-pedicled expanded forehead flap. Annals of plastic surgery. 2009, 63(6):640-4.

  24. Outer Fascia of Orbicularis Oculi Muscle (OFOOM)-Orbicularis (OOM)-Aponeurosis Fixation Approach in Double-Eyelid Blepharoplasty Revision. Aesth Plast Surg https://doi.org/10.1007/s00266-023-03731-2.

  25.基于逆行設(shè)計方法的陰莖頭成形術(shù)在陰莖再造中的臨床應用。2023.39(6):621-627.

  26.眼輪匝肌淺深層肌膜釋放和眶隔高位重置在切開重瞼術(shù)中的應用,中華整形外科雜志2019,35(6):533-537。

  27.耳后皮膚頭皮聯(lián)合擴張皮瓣鬢角再造術(shù),中華整形外科雜志, 2019,35(5):425-429。

  28.股部交腿擴張皮瓣技術(shù)在修復全足底大面積軟組織缺損中的應用,中華整形外科雜志。2020,36(7):780-783,DOI: 10.3760/cma.j.cn114453-20200402-00199

  29.真皮筋膜肌肉懸吊在上瞼皮膚提升和隆眉弓中的應用,中華醫(yī)學美學美容雜志,2019,25(6)468-470.

  30.皮瓣復合肌肉功能性陰莖再造術(shù)的臨床前研究。 《中華整形外科雜志》 , 2016 , 32 (5) :354-358

  31.應用人自體血清培養(yǎng)人口腔黏膜上皮的實驗研究. 中華整形外科雜志,2006,22(1):63-67.

  32.自體血清與胎牛血清培養(yǎng)口腔粘膜角質(zhì)細胞及上皮組織的實驗研究. 中國修復重建外科雜志,2006年,20(3):124。

  33纖維蛋白凝膠移植培養(yǎng)口腔黏膜細胞的研究.中華實驗外科雜志.2008,25(4):440-442.

  34.粉防己堿抑制增生性瘢痕中成纖維細胞增殖的研究.現(xiàn)代康復,2001,5(2):56-57。

  35.角質(zhì)形成細胞培養(yǎng)基培養(yǎng)毛乳頭細胞的實驗研究. 中國修復重建外科雜志, 2010, 24(2):138-142.

  36.毛乳頭細胞在組織工程毛囊構(gòu)建中的應用. 中華醫(yī)學雜志, 2010,90(6):427-429.

  37.高效的毛乳頭細胞分離培養(yǎng)方法. 中國美容整形外科雜志,2010, 21(4):212-215.

  38.乳頭細胞核表皮細胞構(gòu)建帶附屬器的組織工程皮膚.組織工程與重建外科雜志,2011,7(6):301-306.

  39.應用頰肌黏膜瓣修復腭裂術(shù)后裸露骨面的臨床研究.《中國美容醫(yī)學雜志》 , 2017 , 26 (3) :28-30。

  40.臀部美學及擴大整形術(shù)研究進展。《中國美容醫(yī)學》 , 2015 , 24 (18) :81-85

  41.橫形股薄肌肌皮瓣在乳房再造中的應用研究現(xiàn)狀,《組織工程與重建外科》 , 2015 , 11 (6) :396-399。

  42.切開法重瞼成形術(shù)的研究進展.中國美容整形外科雜志,2020,31(5):284-287.

  43.主譯著作一部《東亞人面部美容手術(shù)學》。北京大學醫(yī)學出版社,2009.01

  44.參加編寫《中華醫(yī)學百科全書整形美容外科學》、《尿道下裂學》、《埋沒導引縫合技術(shù)》、《實用尿道下裂手術(shù)》。

  45. 參與《中國皮膚基底細胞癌診療專家指南231016》撰寫。

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